Details
Description
Human HLA-B27
DNA Fluorescence Diagnostic Kit (PCR-Fluorescence Probing)
Human leukocyte antigens are proteins that help the body’s immune system identify its own cells and distinguish between “self’ and “nonself.” Everyone has an inherited combination of HLA genes that code for the many antigens present on the surfaces of their cells. The
presence or absence of each antigen creates a distinctive HLA combination for each person. People with HLA-B27 have an increased likelihood of developing autoimmune diseases such as ankylosing spondylitis (AS), juvenile rheumatoid arthritis URA), reactive arthritis (of which one subset is Reiter syndrome), and isolated acute anterior uveitis. HLA-B27 has also been linked with inflammatory bowel disease and a range of other chronic conditions.
Product Performance
- Methodology: ARMS-PCR
- Sample Type: Peripheral blood
- Sample Input Volume: SnglµL-40ng/µL, 2µL
- Genotype Coverage: Over 200 genotypes
Features & Advantages
- Easy-to-use
- Rapid Turn-round Time
- Internal Control Monitor
- Full Automation Enabled
Application
- It is primarily used to help strengthen or confirm a suspected diagnosis of ankylosing spondylitis (AS), reactive arthritis, juvenile rheumatoid arthritis URA), or sometimes anterior uveitis.
- It can be used as part of a group of tests used to help diagnose and evaluate conditions causing arthritis-like chronic joint pain, stiffness, and inflammation.
- It can be used to help evaluate someone with recurrent uveitis that is not caused by a recognizable disease process.
